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Scientist - Ophthalmology

Company Name:
Crespo, Serin
Job Summary and Essential Functions:
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron markets medicines for eye diseases, colorectal cancer, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including hypercholesterolemia, oncology, rheumatoid arthritis, allergic asthma, and atopic dermatitis.
Summary:
This individual will be the key internal Ophthalmology Research scientist supporting the design and creation of viral vectors for genetic manipulation of experimental animals for the group. They will be responsible for the design and creation of viruses for biological experiments necessary to develop animal models and deliver experimental therapeutic proteins. This individual will also help implement these in vivo experiments, and provide in-house technical expertise for interacting with external collaborators on gene therapy projects.
Responsibilities:
Designing, cloning and packaging of AAV and Lenti-viral vectors.
Design of micro-RNA and shRNA vectors.
Cell culture of lines and primary cells.
Quality assessment of vectors and gene expression.
PREFERRED FUNCTIONS
Animal models of eye diseases, in vivo procedures eg intravitreal, sub-retinal, intra-peritoneal and subcutaneous injections, oral gavage, blood collection
Animal breeding, Genotyping, RT-PCR, ELISA, immunoblotting, immunoprecipitation, immunocytochemistry, cryo-sections, histology and immunohistochemistry
Confocal and fluorescence microscopy. Electroretinogram (ERG), Spectral domain Optical Coherence tomography (SD-OCT), Scanning Laser Ophthalmoscopy.
Experience and Required Skills:
Requirements:
This position requires advanced degree, PhD and/or MD with atleast 2 years post-doctoral experience .
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regenerons unwavering commitment to combining good science & good business.
To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Apply online at:
http://careers.regeneron.com/united-states/scientist/jobid5438045-scientist-jobs

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